海水提铀、碳酸氢铵、夹心免疫测定等

ZHONGKEHUANCAI

中稿作品解读

标题

Uranium extraction from seawater: material design, emerging technologies and marine engineering

DOI

https://doi.org/10.1002/anie.202206825

作者

Yi Xie, Zeyu Liu, Yiyun Geng, Hao Li, Ning Wang, Yanpei Song, Xiaolin Wang, Jing Chen, Jianchen Wang, Shengqian and GangYe.

从海水中提取铀（UES）是确保铀长期供应和核能可持续性的一种潜在方法，在过去十年中取得了重大进展。通过各种创新的合成策略，开发了具有创纪录高容量的有前途的吸附剂，一些国家已经提出了扩大海洋现场试验的规模。然而，在吸附剂在复杂海洋环境中的特性、部署方法以及当前UES系统的经济可行性方面仍然存在重大挑战。

本文综述了UES领域的最新进展，重点介绍了UES的机理基础以及以功能为导向开发具有高吸附能力、选择性、耐生物淤积性和耐久性的铀吸附剂的方法的新见解。一个特别的重点是新兴的电化学和光化学策略，这些策略已被用于开发高效的UES系统。总结了主要国家在海洋试验方面的最新成就；讨论了与UES的基础，技术和工程方面相关的挑战和观点。这项审查旨在激发创新理念，并为开发技术和经济上可行的UES系统提供技术解决方案。

中稿作品·本周精选

ZHONGKEHUANCAI

01

Volume 94, Issue 51 December 27, 2022

标题

Minimum Distance Between Two Epitopes in Sandwich Immunoassays for Small Molecules

DOI

https://doi.org/10.1021/acs.analchem.2c03592

Abstract（上下滑动查看）

The pursuit of the limit between dimensionalities is a scientific goal with high applicability. Sandwich immunoassay, usually based on two antibodies binding two epitopes, is one of the most popular mainstay tools in both academic and industrial fields. Herein, we determined and evaluated the minimum distance of two epitopes in sandwich immunoassays for small molecules. Briefly, nine model analytes comprising two hapten epitopes, that is, melamine (MEL) and p-nitroaniline (NIA), were designed by increasing the linear chain linkers brick by brick. Two groups of monoclonal antibodies (mAbs) were produced with different recognition properties toward MEL and NIA using 12 new haptens with different spacer arms. The results indicated that two epitopes of the analyte with a distance of only 2.4 Å could be simultaneously bound by two mAbs, which is the known limit of epitope distance in sandwich immunoassays thus far. We further found that an epitope distance of below 8.8 Å for the analyte generally induces noticeable steric hindrance of antibodies, preventing a sandwich immunoassay with high probability. These observations were investigated and evaluated by molecular docking, molecular dynamics, and surface plasmon resonance and using model and real analytes. Altogether, we determined the minimum distance of two epitopes and explored the molecular mechanism of the antibody–analyte–antibody ternary complex in sandwich immunoassays, providing a theoretical basis for hapten design, antibody discovery and development, and sandwich immunoassay establishment for small molecules.

02

Volume 127, Issue 1 January 12, 2023

标题

Biaxial Hard Compression, Anisotropic Elastic Property, and Pressure-Induced Isosymmetric Phase Transition in Ammonium Bicarbonate

DOI

https://doi.org/10.1021/acs.jpcc.2c07967

Abstract（上下滑动查看）

The elastic property, exceptional anisotropic compression, and pressure-induced isosymmetric phase transition in ammonium bicarbonate (AB) are studied by in situ synchrotron X-ray diffraction, Raman spectroscopy, and computational methods. The exceptional anisotropic compression as a result of biaxial hard compression is induced by stiff hydrogen-bonding “double-wine-rack” geometric motifs. The large values of elastic anisotropy such as Young’s moduli, Shear moduli, and Poisson’s ratio verify the anisotropic nature in AB. The biaxial hard compression further induces an isosymmetric phase transition at 2 GPa through the generation of new N–H···O hydrogen bonds. Our work first demonstrates the stiff mechanical study of “double-wine-rack” geometric hydrogen-bonding networks and its influence on the phase transition, which can be used as a model to investigate the robust nature of hydrogen bonds and the structural origin of isosymmetric phase transition. Moreover, the hydrogen-bonding “double-wine-rack” geometric mechanism also provides an inspiration to construct a covalent-bonding “double-wine-rack” geometric model favoring anomalous biaxial mechanical/thermal responses. The determination of the high-pressure phase of AB provides new information to understand the composition of the ternary system H2O–CO2–NH3.

03

Volume 7, Issue 4 December 2022

04

Volume39, Issue2 February, 2022

05

Volume2, Issue3 November, 2022

06

Volume11, Issue21 November 2, 2022

标题

Modified Biodegradation Behavior Induced Beneficial Microenvironments for Bone Regeneration by Low Addition of Gadolinium in Zinc

DOI

https://doi.org/10.1002/adhm.202201184

Abstract（上下滑动查看）

Zinc (Zn) shows a great potential as a biodegradable material for bone implants after a decade of systematic research and development. However, uncontrollable biodegradation behavior and biphasic dose-response prevent Zn from fulfilling its essential role in facilitating bone regeneration. In this study, the low addition of gadolinium (Gd) modifies the intrinsic microstructure of Zn in terms of grain size distribution, grain boundary misorientation, and texture. Adding Gd refines grain size distribution and creates a stronger basal plane texture in Zn, consequently, changing the current density distribution and reducing the anode dissolution rate during corrosion. As a result, uniform degradation is more predominant in Zn-0.4Gd alloy implant, in comparison to localized degradation in pure Zn implant in bone environments. The modified biodegradation behavior of the Zn-0.4Gd alloy implant induces significantly better new bone formation and osseointegration compared to the pure Zn implant. Therefore, Gd with trace amounts is able to tune the degradation behavior and improve the performance of Zn-based implants in promoting bone regeneration.

07

Volume36, Issue6 December, 2022

标题

Pressure Effects on the Tetragonal FeS Superconductor

DOI

http://www.gywlxb.cn/cn/article/doi/10.11858/gywlxb.20220677

Abstract（上下滑动查看）

High-pressure regulation has played an important role in enhancing the superconducting transition temperature (Tc) and revealing the competing electronic orders and superconducting mechanisms of iron-based superconductors. A large number of high-pressure studies have shown that different pressure conditions (hydrostatic vs. non-hydrostatic pressure) can make great differences in the physical properties of condensed matters under high pressure. To unveil the discrepancies of different high-pressure studies on tetragonal FeS, we performed high-pressure magnetic susceptibility and resistivity measurements on tetragonal FeS single crystal up to 11 GPa by using a piston-cylinder and a cubic anvil cell that can produce good hydrostatic pressures. It is found that its Tc decreases monotonically with increasing pressure with a slope of dTc/dp≈−1.5 K/GPa, which indicates that the superconductivity can be completely suppressed at about 3 GPa. When the tetragonal-hexagonal structural phase transition occurs at about 4−5 GPa, the temperature-dependent resistivity changes from metallic to semiconducting behavior, and the resistivity shows continuous increase upon further increasing pressure. No second superconducting phase was observed up to 11 GPa, and our results thus do not support the conclusion that FeS has two superconducting phases at high pressure. Finally, in light of the structural information under pressure, we discussed briefly the underlying mechanism for the distinct pressure evolutions of the physical properties in FeS and FeSe.

08

Volume11, Issue21 November 2, 2022

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